💊 Drug Reference
100 drug profiles — mechanism, indications, contraindications and MLA prescribing safety
100 drugs
Angiotensin-converting enzyme (ACE) inhibitors are a class of cardiovascular med
ACE inhibitors are widely used for the management of essential hypertension, particularly …
MLA DrugAngiotensin Receptor Blockers (ARBs), also known as sartans, are a class of card
ARBs are indicated for the treatment of essential hypertension, especially in patients int…
MLA DrugBeta blockers are a class of medications that block beta-adrenergic receptors, p
Beta blockers are widely used for hypertension, particularly in younger patients or those …
MLA DrugDihydropyridine calcium channel blockers (DHP-CCBs) are a class of cardiovascula
DHP-CCBs are a first-line treatment for essential hypertension, particularly in older pati…
MLA DrugNon-dihydropyridine calcium channel blockers (non-DHP CCBs) are a class of cardi
Non-DHP CCBs are primarily used for rate control in supraventricular tachyarrhythmias like…
MLA DrugLoop diuretics are a class of potent diuretics that act on the thick ascending l
Loop diuretics are indicated for the treatment of oedema associated with heart failure, li…
MLA DrugThiazide diuretics are a class of diuretics that act on the distal convoluted tu
Thiazide diuretics are a first-line treatment for essential hypertension, particularly in …
MLA DrugPotassium-sparing diuretics are a class of diuretics that increase diuresis with
Potassium-sparing diuretics are indicated for the treatment of oedema and ascites associat…
MLA DrugStatins, or HMG-CoA reductase inhibitors, are a class of lipid-lowering medicati
Statins are indicated for the primary prevention of cardiovascular disease in individuals …
MLA DrugEzetimibe is a selective cholesterol absorption inhibitor, often used as an adju
Ezetimibe is indicated for primary hypercholesterolaemia, either as monotherapy in patient…
MLA DrugFibrates are a class of lipid-lowering drugs primarily used to reduce elevated t
Fibrates are indicated for severe hypertriglyceridaemia, particularly when there is a risk…
MLA DrugNitrates are a class of vasodilators used primarily for the treatment and preven
They are indicated for the acute relief of angina pectoris (e.g., sublingual glyceryl trin…
MLA DrugNicorandil is an anti-anginal drug that acts as a potassium channel activator an
Nicorandil is indicated for the prevention and long-term treatment of stable angina pector…
MLA DrugIvabradine is a selective and specific inhibitor of the 'funny' current (If) in
Ivabradine is indicated for the symptomatic treatment of chronic stable angina pectoris in…
MLA DrugDigoxin is a cardiac glycoside derived from the foxglove plant, primarily used t
Digoxin is indicated for the control of ventricular rate in chronic atrial fibrillation, e…
MLA DrugAspirin is a non-steroidal anti-inflammatory drug (NSAID) and an antiplatelet ag
Low-dose aspirin is primarily used for secondary prevention of atherothrombotic events, su…
MLA DrugClopidogrel is an antiplatelet agent belonging to the thienopyridine class. It i
Clopidogrel is used for the prevention of atherothrombotic events in patients with a histo…
MLA DrugTicagrelor is an antiplatelet agent, specifically a direct-acting, reversible P2
Ticagrelor is indicated for the prevention of atherothrombotic events in adult patients wi…
MLA DrugDipyridamole is an antiplatelet agent and a vasodilator. It is often used in com
Dipyridamole, usually in modified-release formulation combined with aspirin, is indicated …
MLA DrugWarfarin is an oral anticoagulant belonging to the coumarin class. It acts as a
Warfarin is indicated for the prevention and treatment of venous thromboembolism (VTE), in…
MLA DrugDOACs are a class of oral anticoagulant medications that directly inhibit specif
DOACs are primarily used for the prevention of stroke and systemic embolism in patients wi…
MLA DrugLow Molecular Weight Heparins (LMWHs) are a class of anticoagulant medications d
LMWHs are widely used for the prophylaxis of venous thromboembolism (VTE) in surgical and …
MLA DrugUnfractionated Heparin (UFH) is a rapidly acting parenteral anticoagulant that i
UFH is used for the acute treatment of deep vein thrombosis (DVT) and pulmonary embolism (…
MLA DrugFondaparinux is a synthetic selective Factor Xa inhibitor, belonging to the clas
Fondaparinux is indicated for the prophylaxis of venous thromboembolism (VTE) in patients …
MLA DrugTranexamic acid is an antifibrinolytic agent that inhibits fibrinolysis, thereby
Tranexamic acid is widely used to reduce bleeding in various clinical settings, including …
MLA DrugAdenosine is an endogenous nucleoside that acts as an antiarrhythmic agent, prim
The primary indication for adenosine is the rapid termination of paroxysmal supraventricul…
MLA DrugAmiodarone is a Class III antiarrhythmic agent, according to the Vaughan William
Amiodarone is used for a wide range of supraventricular and ventricular arrhythmias, parti…
MLA DrugFlecainide is a Class Ic antiarrhythmic agent, according to the Vaughan Williams
Flecainide is primarily used for the treatment of paroxysmal supraventricular tachycardias…
MLA DrugSotalol is a unique antiarrhythmic agent classified as a Class III antiarrhythmi
Sotalol is used for the treatment of various supraventricular and ventricular arrhythmias.…
MLA DrugAtropine is an anticholinergic (antimuscarinic) agent, belonging to the class of
The primary indication for atropine is the treatment of symptomatic bradycardia, particula…
MLA DrugInsulin is a hormone replacement therapy, a polypeptide hormone produced by the
Insulin is indicated for all patients with Type 1 Diabetes Mellitus. In Type 2 Diabetes Me…
MLA DrugMetformin is a biguanide, an oral antihyperglycaemic agent and the first-line ph
Metformin is the first-line drug for Type 2 Diabetes Mellitus, especially in those who are…
MLA DrugSulfonylureas are oral antihyperglycaemic agents used in the management of Type
Sulfonylureas are indicated for Type 2 Diabetes Mellitus when diet and exercise alone are …
MLA DrugDPP-4 inhibitors (gliptins) are oral antihyperglycaemic agents used in the manag
DPP-4 inhibitors are indicated for Type 2 Diabetes Mellitus, typically as a second-line ag…
MLA DrugGLP-1 Receptor Agonists (incretin mimetics) are injectable antihyperglycaemic ag
GLP-1 receptor agonists are indicated for Type 2 Diabetes Mellitus, usually as a second or…
MLA DrugSGLT2 inhibitors (sodium-glucose co-transporter 2 inhibitors) are a class of ora
Primarily indicated for the treatment of type 2 diabetes mellitus, often as an add-on ther…
MLA DrugThiazolidinediones (TZDs), also known as glitazones, are a class of oral antidia
Primarily used in type 2 diabetes mellitus, often as an add-on therapy, particularly in pa…
MLA DrugLevothyroxine is a synthetic preparation of thyroxine (T4), the primary hormone
The primary indication is for the treatment of hypothyroidism, regardless of its cause (e.…
MLA DrugCarbimazole is an antithyroid drug, a pro-drug that is metabolised to methimazol
Primarily indicated for the treatment of hyperthyroidism, including Graves' disease, toxic…
MLA DrugPropylthiouracil (PTU) is an antithyroid drug, belonging to the thionamide class
Primarily indicated for the treatment of hyperthyroidism, particularly in patients who can…
MLA DrugHydrocortisone is a short-acting glucocorticoid, a type of corticosteroid. It is
Hydrocortisone is used for physiological replacement in adrenal insufficiency (e.g., Addis…
MLA DrugPrednisolone is an intermediate-acting synthetic glucocorticoid, a type of corti
Prednisolone is widely used for its anti-inflammatory and immunosuppressive properties in …
MLA DrugDexamethasone is a potent, long-acting synthetic glucocorticoid, a type of corti
Dexamethasone is used in conditions requiring potent and prolonged corticosteroid action, …
MLA DrugFludrocortisone is a synthetic corticosteroid with potent mineralocorticoid acti
Fludrocortisone is primarily used for replacement therapy in primary adrenal insufficiency…
MLA DrugNon-Steroidal Anti-Inflammatory Drugs (NSAIDs) are a class of medications that r
NSAIDs are widely used for the symptomatic relief of mild to moderate pain, such as headac…
MLA DrugParacetamol is an analgesic and antipyretic agent, often classified as a non-opi
Paracetamol is indicated for the relief of mild to moderate pain, including headache, musc…
MLA DrugWeak opioids are a class of analgesic drugs used for moderate pain relief. They
These drugs are indicated for the management of moderate pain when non-opioid analgesics a…
MLA DrugStrong opioids are potent analgesic drugs primarily used for the management of s
Strong opioids are indicated for the relief of severe pain, such as that associated with c…
MLA DrugNaloxone is a pure opioid antagonist. It rapidly reverses the effects of opioid
Naloxone is indicated for the complete or partial reversal of opioid-induced respiratory d…
MLA DrugLocal anaesthetics are a class of drugs that reversibly block nerve conduction w
Local anaesthetics are used for various procedures requiring localised pain control, such …
MLA DrugSelective Serotonin Reuptake Inhibitors (SSRIs) are a class of antidepressant me
Major Depressive Disorder is a primary indication. They are also widely used for anxiety d…
MLA DrugSerotonin-Noradrenaline Reuptake Inhibitors (SNRIs) are a class of antidepressan
Major Depressive Disorder is a primary indication. They are also used for Generalised Anxi…
MLA DrugTricyclic Antidepressants (TCAs) are an older class of antidepressant medication
While largely superseded by newer antidepressants, TCAs are still used for severe depressi…
MLA DrugMirtazapine is a noradrenergic and specific serotonergic antidepressant (NaSSA).
Mirtazapine is primarily indicated for the treatment of major depressive disorder. It is o…
MLA DrugMonoamine Oxidase Inhibitors (MAOIs) are an older class of antidepressants that
MAOIs are generally reserved for atypical depression, treatment-resistant depression, or w…
MLA DrugTypical antipsychotics, also known as first-generation antipsychotics, are a cla
Typical antipsychotics are indicated for the treatment of acute and chronic schizophrenia,…
MLA DrugAtypical antipsychotics, or second-generation antipsychotics, are a class of med
Atypical antipsychotics are first-line treatment for schizophrenia and other psychotic dis…
MLA DrugLithium is a mood stabiliser, primarily used in the treatment of bipolar disorde
Lithium is primarily indicated for the prophylaxis of bipolar affective disorder, reducing…
MLA DrugClozapine is an atypical antipsychotic, unique in its efficacy for treatment-res
Clozapine is exclusively indicated for treatment-resistant schizophrenia, defined as inade…
MLA DrugBenzodiazepines are a class of psychoactive drugs that are central nervous syste
Benzodiazepines are indicated for the short-term management of severe anxiety, insomnia (w…
MLA DrugZ-drugs are a class of non-benzodiazepine hypnotics, primarily used for the shor
Zopiclone is indicated for the short-term treatment of insomnia, particularly when the ins…
MLA DrugSodium valproate is a broad-spectrum antiepileptic drug (AED) and a mood stabili
Sodium valproate is indicated for the treatment of generalised, partial, and myoclonic sei…
MLA DrugCarbamazepine is an antiepileptic drug (AED) and a mood stabiliser, structurally
Carbamazepine is a first-line treatment for focal (partial) seizures, with or without seco…
MLA DrugLamotrigine is an antiepileptic drug (AED) and a mood stabiliser, often used as
Lamotrigine is indicated for focal (partial) seizures and generalised tonic-clonic seizure…
MLA DrugLevetiracetam is a broad-spectrum antiepileptic drug (AED) with a unique mechani
Levetiracetam is indicated for the treatment of focal (partial) seizures, myoclonic seizur…
MLA DrugPhenytoin is an antiepileptic drug, classified as a hydantoin derivative. It is
Phenytoin is used for the treatment of tonic-clonic seizures and focal (partial) seizures.…
MLA DrugTopiramate is an antiepileptic drug, often referred to as a broad-spectrum antic
Topiramate is indicated for the treatment of focal (partial) seizures and primary generali…
MLA DrugLevodopa is a dopamine precursor and the most effective symptomatic treatment fo
Levodopa is the primary treatment for motor symptoms in Parkinson's disease, particularly …
MLA DrugDopamine agonists are a class of drugs that directly stimulate dopamine receptor
Dopamine agonists are used as monotherapy in early Parkinson's disease to delay the need f…
MLA DrugMonoamine oxidase B (MAO-B) inhibitors are a class of drugs used in the treatmen
MAO-B inhibitors are used as monotherapy in early Parkinson's disease to provide symptomat…
MLA DrugCOMT inhibitors are a class of drugs used in the management of Parkinson's disea
COMT inhibitors are indicated for the treatment of Parkinson's disease as an adjunct to le…
MLA DrugAnticholinergics are a class of drugs that block the action of acetylcholine. In
Anticholinergics are primarily indicated for the treatment of drug-induced parkinsonism, o…
MLA DrugShort-acting beta-2 agonists (SABAs) are a class of bronchodilator medications u
SABAs are indicated for the rapid relief of asthma symptoms, such as wheezing, breathlessn…
MLA DrugLong-acting beta-2 agonists (LABAs) are bronchodilator medications that provide
LABAs are indicated as maintenance therapy for asthma, always in combination with an inhal…
MLA DrugInhaled corticosteroids (ICS) are anti-inflammatory medications delivered direct
ICS are indicated as first-line maintenance therapy for persistent asthma of all severitie…
MLA DrugLAMAs are bronchodilators used in the management of chronic obstructive pulmonar
The primary indication for LAMAs in the UK is the maintenance treatment of chronic obstruc…
MLA DrugSAMAs are bronchodilators primarily used for the rapid relief of bronchospasm in
The main indication for SAMAs in the UK is the relief of acute bronchospasm in chronic obs…
MLA DrugLeukotriene Receptor Antagonists (LTRAs) are a class of medications used in the
LTRAs are primarily indicated as an add-on therapy for the maintenance treatment of mild t…
MLA DrugTheophylline is a methylxanthine bronchodilator used in the management of chroni
In the UK, theophylline is typically reserved for severe, persistent asthma or COPD that r…
MLA DrugPenicillins are a broad class of beta-lactam antibiotics, derived from the Penic
Penicillins are indicated for a wide range of bacterial infections, including respiratory …
MLA DrugCephalosporins are a class of beta-lactam antibiotics, structurally and pharmaco
They are widely used for a variety of bacterial infections, including respiratory tract in…
MLA DrugMacrolides are a class of bacteriostatic antibiotics characterised by a large ma
They are commonly used for respiratory tract infections, including community-acquired pneu…
MLA DrugTetracyclines are a class of broad-spectrum bacteriostatic antibiotics. They are
They are used for various infections, including acne vulgaris, rosacea, community-acquired…
MLA DrugAminoglycosides are a class of bactericidal antibiotics primarily effective agai
They are typically reserved for serious Gram-negative infections, including septicaemia, c…
MLA DrugFluoroquinolones are a class of broad-spectrum bactericidal antibiotics. They ar
They are typically reserved for serious infections where other antibiotics are unsuitable,…
MLA DrugVancomycin is a glycopeptide antibiotic, a class of antimicrobials primarily use
Vancomycin is a crucial antibiotic for methicillin-resistant Staphylococcus aureus (MRSA) …
MLA DrugMetronidazole is a nitroimidazole antibiotic and antiprotozoal agent, effective
Metronidazole is widely used for anaerobic bacterial infections, including intra-abdominal…
MLA DrugTrimethoprim is a folate antagonist antibiotic. Co-trimoxazole is a combination
Trimethoprim is primarily used for uncomplicated urinary tract infections (UTIs) in the UK…
MLA DrugNitrofurantoin is a nitrofuran antibiotic, specifically used for the treatment a
Nitrofurantoin is a first-line agent for uncomplicated lower urinary tract infections (UTI…
MLA DrugAzole antifungals are a broad class of synthetic antifungal agents, including bo
Azoles are used for a wide range of fungal infections. Fluconazole is common for candidias…
MLA DrugEchinocandins are a class of antifungal drugs, often referred to as 'penicillin
Echinocandins are primarily indicated for invasive candidiasis, including candidaemia, and…
MLA DrugAciclovir is an antiviral drug, specifically a synthetic purine nucleoside analo
Aciclovir is indicated for the treatment of herpes simplex infections of the skin and muco…
MLA DrugOseltamivir is an antiviral drug belonging to the class of neuraminidase inhibit
Oseltamivir is indicated for the treatment of influenza in adults and children who present…
MLA DrugAntiretrovirals (ARVs) are a diverse group of drugs used in combination to treat
Antiretroviral therapy (ART) is indicated for all individuals diagnosed with HIV infection…
MLA DrugMethotrexate is an antimetabolite, specifically a folic acid antagonist. It is u
In low doses, methotrexate is a cornerstone treatment for rheumatoid arthritis, psoriatic …
MLA DrugSulfasalazine is an aminosalicylate derivative, often classified as a disease-mo
In the UK, sulfasalazine is primarily used for inflammatory bowel disease (IBD), particula…
MLA DrugHydroxychloroquine is an antimalarial drug with significant immunomodulatory and
In the UK, it is widely used for systemic lupus erythematosus (SLE), particularly for skin…
MLA DrugAzathioprine is an immunosuppressant drug, classified as an antimetabolite. It i
In the UK, it is widely used for organ transplant rejection prophylaxis, often in combinat…
MLA DrugCiclosporin is a calcineurin inhibitor, classified as an immunosuppressant. It i
In the UK, its primary use is for the prophylaxis of organ transplant rejection (kidney, l…
MLA DrugTacrolimus is a macrolide lactone, classified as a calcineurin inhibitor and a p
In the UK, its primary use is for the prophylaxis of organ transplant rejection (kidney, l…
MLA Drug