Sepsis

Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. …

⚠️ Deterioration in conscious level (e.g., GCS drop by 2 points), persistent hypote
Emergency
Septic Shock

Septic shock is a subset of sepsis with circulatory and cellular/metabolic dysfunction associated wi…

⚠️ Failure to respond to vasopressors, increasing vasopressor requirements, worseni
Emergency
Anaphylaxis

Anaphylaxis is a severe, life-threatening, generalised or systemic hypersensitivity reaction. It is …

⚠️ Any signs of airway compromise (e.g., worsening stridor, hoarseness), persistent
Emergency
Airway Obstruction

Airway obstruction is a life-threatening emergency where the passage of air to the lungs is partiall…

⚠️ Complete absence of breath sounds, inability to speak or cough, cyanosis, rapidl
Emergency
Acute Severe Asthma

Acute severe asthma is a medical emergency characterised by rapidly worsening asthma symptoms that a…

⚠️ Deterioration to life-threatening asthma (silent chest, cyanosis, exhaustion, al
Emergency
Life-threatening COPD Exacerbation

A severe, acute worsening of COPD symptoms requiring urgent medical intervention, often precipitated…

⚠️ Worsening confusion or drowsiness, decreasing oxygen saturation despite high-flo
Emergency
Tension Pneumothorax

A life-threatening condition where air enters the pleural space but cannot escape, leading to progre…

⚠️ Rapidly deteriorating oxygen saturation, increasing respiratory distress, progre
Emergency
Massive Pulmonary Embolism

A life-threatening condition caused by a large blood clot obstructing a major pulmonary artery, lead…

⚠️ Persistent hypotension (systolic BP <90 mmHg or drop >40 mmHg from baseline), pe
Emergency
Acute Coronary Syndrome

A spectrum of conditions including unstable angina, NSTEMI, and STEMI, resulting from acute myocardi…

⚠️ Persistent or worsening chest pain despite initial therapy, new or worsening hae
Emergency
Cardiac Arrest

The sudden cessation of cardiac mechanical activity, confirmed by the absence of signs of circulatio…

⚠️ Any patient who becomes unresponsive and stops breathing normally. Deterioration
Emergency
Bradyarrhythmias

Bradyarrhythmias are abnormally slow heart rhythms, typically defined as <60 bpm, which can lead to …

⚠️ Persistent hypotension (systolic BP <90 mmHg), signs of shock (cool peripheries,
Emergency
Tachyarrhythmias

Tachyarrhythmias are abnormally fast heart rhythms, typically >100 bpm, which can compromise cardiac…

⚠️ Haemodynamic instability is paramount: systolic BP <90 mmHg, signs of shock (coo
Emergency
Hypertensive Emergency

Hypertensive emergency is defined as severe hypertension (typically systolic >180 mmHg or diastolic …

⚠️ Any evidence of new or worsening target organ damage: acute neurological changes
Emergency
Shock

Shock is a life-threatening condition of circulatory failure leading to inadequate tissue perfusion …

⚠️ Persistent hypotension despite fluid resuscitation, worsening altered mental sta
Emergency
Major Trauma

Major trauma is severe injury to multiple body regions or a single severe injury that can result in …

⚠️ Deterioration in GCS, persistent hypotension despite fluid resuscitation, uncont
Emergency
Head Injury

Head injury encompasses any trauma to the head, ranging from minor scalp lacerations to severe brain…

⚠️ Decreasing GCS score, new focal neurological deficit, pupillary asymmetry, persi
Emergency
Raised Intracranial Pressure

Raised intracranial pressure (ICP) occurs when the volume of intracranial contents (brain, blood, CS…

⚠️ Rapidly deteriorating GCS, new pupillary asymmetry or unreactivity, new focal ne
Emergency
Status Epilepticus

Status epilepticus is defined as a seizure lasting longer than 5 minutes, or recurrent seizures with…

⚠️ Seizure duration exceeding 5 minutes, failure to respond to initial benzodiazepi
Emergency
Acute Stroke

Acute stroke is a sudden neurological deficit caused by ischaemia (85%) or haemorrhage (15%) in the …

⚠️ Rapidly worsening neurological deficits, signs of raised ICP (e.g., headache, vo
Emergency
Subarachnoid Haemorrhage

Subarachnoid haemorrhage (SAH) is bleeding into the subarachnoid space, typically caused by rupture …

⚠️ Decreasing GCS, new focal neurological deficits, pupillary changes, seizures, si
Emergency
Meningococcal Disease

Meningococcal disease is a life-threatening bacterial infection, most commonly caused by Neisseria m…

⚠️ Rapidly spreading or extensive purpuric rash, signs of septic shock (hypotension
Emergency
Hyperkalaemia

Hyperkalaemia is a potentially life-threatening electrolyte disturbance defined as a serum potassium…

⚠️ ECG changes (peaked T waves, prolonged PR interval, widened QRS, absent P waves,
Emergency
Diabetic Ketoacidosis

Diabetic Ketoacidosis (DKA) is a life-threatening complication of diabetes, characterised by hypergl…

⚠️ Persistent or worsening acidosis despite treatment, rapidly decreasing GCS, sign
Emergency
Hyperosmolar Hyperglycaemic State

Hyperosmolar Hyperglycaemic State (HHS), previously known as HONK, is a severe, life-threatening com…

⚠️ Profound dehydration with signs of hypovolaemic shock, rapidly decreasing GCS, s
Emergency
Adrenal Crisis

Adrenal crisis (acute adrenal insufficiency) is a life-threatening endocrine emergency caused by an …

⚠️ Refractory hypotension despite fluid resuscitation, rapidly decreasing GCS, seve
Emergency
Acute Kidney Injury

Acute Kidney Injury (AKI) is a sudden decline in renal function, leading to accumulation of waste pr…

⚠️ Red flags include severe oliguria/anuria, hyperkalaemia (especially with ECG cha
Emergency
Upper GI Bleed

An Upper GI Bleed (UGIB) is bleeding originating proximal to the ligament of Treitz, commonly caused…

⚠️ Red flags include persistent hypotension (systolic BP <90 mmHg), tachycardia (>1
Emergency
Poisoning and Overdose

Poisoning and overdose involve exposure to a substance that causes toxicity, either accidental or in…

⚠️ Red flags include reduced GCS (especially <8), respiratory depression (bradypnoe
Emergency
Alcohol Withdrawal

Alcohol withdrawal syndrome occurs when heavy, prolonged alcohol use is suddenly reduced or stopped.…

⚠️ Red flags include seizures, delirium tremens, severe agitation, hyperthermia, si
Emergency
Acute Behavioural Disturbance

Acute Behavioural Disturbance (ABD) is a state of altered consciousness and/or behaviour that poses …

⚠️ Red flags include rapid deterioration in GCS, respiratory compromise, haemodynam
Emergency